Revista Hospital Clínico Universidad de Chile

Resúmenes Jornadas de Investigación 2024

Paul Délano R. — 2025-04-08

No abstract available

Editorial

Paul Délano R. — 2025-04-08

No abstract available

Amiloidosis con compromiso cardíaco, hepático e intestinal: caso clínico

Javier Delgado D. — 2025-04-08

Amyloidosis is a rare disease characterized by amyloid deposits in tissues, mainly affecting the kidneys and heart. Diagnosis requires positive evidence of amyloid deposits by Congo red staining. It is usually a disease with a poor prognosis due to late diagnosis and advanced involvement in affected organs. This report presents the case of a 62-year-old woman with a history of recently diagnosed chronic liver damage, which was notable in the liver profile for elevated alkaline phosphatase, hepatomegaly without splenomegaly, and an unknown etiological study. She was admitted in the context of septic shock with an abdominal focus and a history of chronic diarrhea and symptoms of heart failure. During hospitalization, a broad study was carried out with an echocardiographic study suggesting infiltrative disease and biopsies of subcutaneous fat and colon biopsies consistent with amyloidosis. Given the resolution of the septic condition and clinical stability, she was discharged from the hospital with an indication for multidisciplinary outpatient follow-up.

Pseudolinfoma cutáneo secundario a tatuaje: un caso clínico

Carla Montiel G. — 2025-04-08

Tattoos can cause various dermatological complications, such as infections, contact dermatitis, lichenoid reactions, and granulomatous reactions. It is crucial for general practitioners and dermatologists to be informed about these complications to properly prevent, recognize, and treat patients. This is a case of tattoo pseudolymphoma appearing months after the tattoo was done, in the areas corresponding to the red ink. Cutaneous pseudolymphoma is a reactive lymphocytic proliferation that mimics a cutaneous lymphoma. Although the pathophysiology is uncertain, red pigment has been associated with higher complication rates. The lack of specific regulation in Chile and contamination in tattoo inks highlight the need for better standards. The complication presents as papules and plaques that may resolve spontaneously or with treatment. Prevention is recommended through the choice of reputable tattoo artists and safe inks.

Referencia de ginecoobstetricia: doctor, nuestra paciente tiene ampollas

Jorge Contreras A. — 2025-04-08

Gestational pemphigoid (GP) is a rare autoimmune dermatosis that manifests during pregnancy or postpartum, characterized by intensely pruritic vesiculobullous lesions. It typically presents in the second or third trimester, with an estimated incidence of 1 in 20,000 to 1 in 50,000 pregnancies. GP can be associated with fetal complications, such as prematurity and low birth weight. We report the case of a 29-year-old woman in her first pregnancy who was diagnosed with GP following the development of pruritic papules and blisters on her abdomen. Initial treatment with topical and oral corticosteroids led to the resolution of the lesions. The pathogenesis of GP is linked to the production of antibodies targeting the dermal-epidermal junction, resulting in subepidermal blister formation. Diagnosis is based on clinical assessment and confirmed by specific histopathological findings. Differential diagnoses, such as pruritic papules and plaques of pregnancy, must also be considered. While maternal mortality is not increased, the condition requires coordinated management by dermatologists and obstetricians in high-risk settings to ensure close

Test radiológico

Gonzalo Miranda G. — 2025-04-08

No abstract available

Resultado test radiológico

Gonzalo Miranda G. — 2025-04-08

No abstract available

De NAFLD a MAFLD para llegar a MASLD: La nueva nomenclatura de esteatosis hepática metabólica

Daniel Durán A. — 2025-04-08

In 2023, the Delphi method was employed to revise the nomenclature for metabolic steatotic liver disease, resulting in the replacement of the term “metabolic dysfunction associated fatty liver disease (MAFLD)” with “metabolic dysfunction associated steatotic liver disease (MASLD)”. This modification has sparked concerns, criticism, and questions within the scientific community. This review investigates the evolution of terminology over recent decades, with a particular focus on the newly established diagnostic criteria. These criteria are more precise, mitigate the stigmatization associated with the disease, and offer improved alignment with its underlying pathophysiology. As such, this terminological refinement marks a significant advancement in the understanding of steatotic liver disease and presents new challenges for research and therapeutic development.